diff --git a/web/normogen-web/src/components/appointments/AppointmentsManager.tsx b/web/normogen-web/src/components/appointments/AppointmentsManager.tsx
index 7391943..d3ee7b0 100644
--- a/web/normogen-web/src/components/appointments/AppointmentsManager.tsx
+++ b/web/normogen-web/src/components/appointments/AppointmentsManager.tsx
@@ -25,22 +25,32 @@ import DeleteIcon from '@mui/icons-material/Delete';
 import AddIcon from '@mui/icons-material/Add';
 import { format } from 'date-fns';
 import { useAppointmentStore, useAuthStore } from '../../store/useStore';
-import type {
-  Appointment,
-  CreateAppointmentRequest,
-  UpdateAppointmentRequest,
-} from '../../types/api';
+import type { Appointment } from '../../types/api';
 
 const APPT_TYPES = ['in-person', 'telehealth', 'lab', 'test', 'other'];
 const STATUSES = ['upcoming', 'completed', 'cancelled'];
 
+// Domain form type (decrypted fields the UI collects; the store encrypts them).
+interface ApptFormData {
+  title: string;
+  provider: string;
+  appointment_type: string;
+  date_time: string;
+  location?: string;
+  duration_minutes?: number;
+  reason?: string;
+  notes?: string;
+  status?: string;
+  profile_id?: string;
+}
+
 const statusColor = (status: string): 'success' | 'default' | 'error' => {
   if (status === 'upcoming') return 'success';
   if (status === 'cancelled') return 'error';
   return 'default';
 };
 
-const emptyCreate: CreateAppointmentRequest = {
+const emptyCreate: ApptFormData = {
   title: '',
   provider: '',
   appointment_type: 'in-person',
@@ -67,9 +77,9 @@ export const AppointmentsManager: FC = () => {
   const user = useAuthStore((s) => s.user);
 
   const [createOpen, setCreateOpen] = useState(false);
-  const [createForm, setCreateForm] = useState<CreateAppointmentRequest>(emptyCreate);
+  const [createForm, setCreateForm] = useState<ApptFormData>(emptyCreate);
   const [editTarget, setEditTarget] = useState<Appointment | null>(null);
-  const [editForm, setEditForm] = useState<UpdateAppointmentRequest>({});
+  const [editForm, setEditForm] = useState<Partial<ApptFormData>>({});
   const [deleteTarget, setDeleteTarget] = useState<Appointment | null>(null);
   const [saving, setSaving] = useState(false);
 
@@ -88,7 +98,7 @@ export const AppointmentsManager: FC = () => {
   const submitCreate = async () => {
     setSaving(true);
     try {
-      await createAppointment(createForm);
+      await createAppointment(createForm as unknown as Record<string, unknown>);
       setCreateOpen(false);
     } catch {
       /* error surfaced via store */
@@ -116,7 +126,7 @@ export const AppointmentsManager: FC = () => {
     if (!editTarget?.appointment_id) return;
     setSaving(true);
     try {
-      await updateAppointment(editTarget.appointment_id, editForm);
+      await updateAppointment(editTarget.appointment_id, editForm as unknown as Record<string, unknown>);
       setEditTarget(null);
     } catch {
       /* error surfaced via store */
diff --git a/web/normogen-web/src/components/medication/MedicationManager.tsx b/web/normogen-web/src/components/medication/MedicationManager.tsx
index 90f411d..e80679c 100644
--- a/web/normogen-web/src/components/medication/MedicationManager.tsx
+++ b/web/normogen-web/src/components/medication/MedicationManager.tsx
@@ -25,16 +25,23 @@ import EditIcon from '@mui/icons-material/Edit';
 import DeleteIcon from '@mui/icons-material/Delete';
 import AddIcon from '@mui/icons-material/Add';
 import { useMedicationStore, useAuthStore } from '../../store/useStore';
-import type {
-  Medication,
-  CreateMedicationRequest,
-  UpdateMedicationRequest,
-} from '../../types/api';
+import type { Medication } from '../../types/api';
 import { DoseLogger } from './DoseLogger';
 
 const ROUTES = ['oral', 'topical', 'injection', 'inhalation', 'other'] as const;
 
-const emptyCreate: CreateMedicationRequest = {
+// Domain form types (decrypted fields the UI collects; the store encrypts them).
+interface MedFormData {
+  name: string;
+  dosage: string;
+  frequency: string;
+  route: string;
+  instructions?: string;
+  profile_id?: string;
+  active?: boolean;
+}
+
+const emptyCreate: MedFormData = {
   name: '',
   dosage: '',
   frequency: '',
@@ -56,9 +63,9 @@ export const MedicationManager: FC = () => {
   const user = useAuthStore((s) => s.user);
 
   const [createOpen, setCreateOpen] = useState(false);
-  const [createForm, setCreateForm] = useState<CreateMedicationRequest>(emptyCreate);
+  const [createForm, setCreateForm] = useState<MedFormData>(emptyCreate);
   const [editTarget, setEditTarget] = useState<Medication | null>(null);
-  const [editForm, setEditForm] = useState<UpdateMedicationRequest>({});
+  const [editForm, setEditForm] = useState<Partial<MedFormData>>({});
   const [deleteTarget, setDeleteTarget] = useState<Medication | null>(null);
   const [saving, setSaving] = useState(false);
 
@@ -238,7 +245,7 @@ export const MedicationManager: FC = () => {
               fullWidth
               value={createForm.route}
               onChange={(e) =>
-                setCreateForm({ ...createForm, route: e.target.value as CreateMedicationRequest['route'] })
+                setCreateForm({ ...createForm, route: e.target.value })
               }
             >
               {ROUTES.map((r) => (
diff --git a/web/normogen-web/src/crypto/cipher.ts b/web/normogen-web/src/crypto/cipher.ts
index c5f1658..c9a4bb3 100644
--- a/web/normogen-web/src/crypto/cipher.ts
+++ b/web/normogen-web/src/crypto/cipher.ts
@@ -40,9 +40,9 @@ export async function encrypt(
 ): Promise<CipherPayload> {
   const iv = randomIv();
   const ciphertext = await crypto.subtle.encrypt(
-    { name: 'AES-GCM', iv },
+    { name: 'AES-GCM', iv: iv as BufferSource },
     key,
-    encoder.encode(plaintext),
+    encoder.encode(plaintext) as BufferSource,
   );
   return {
     data: b64.encode(new Uint8Array(ciphertext)),
@@ -57,9 +57,9 @@ export async function decrypt(
 ): Promise<string> {
   const iv = b64.decode(payload.iv);
   const plaintext = await crypto.subtle.decrypt(
-    { name: 'AES-GCM', iv },
+    { name: 'AES-GCM', iv: iv as BufferSource },
     key,
-    b64.decode(payload.data),
+    b64.decode(payload.data) as BufferSource,
   );
   return decoder.decode(plaintext);
 }
diff --git a/web/normogen-web/src/services/api.ts b/web/normogen-web/src/services/api.ts
index 3cf213b..ca490d0 100644
--- a/web/normogen-web/src/services/api.ts
+++ b/web/normogen-web/src/services/api.ts
@@ -17,8 +17,10 @@ import {
   DoseLog,
   LogDoseRequest,
   AdherenceStats,
-  Profile,
-  Appointment,
+  MedicationWireResponse,
+  AppointmentWireResponse,
+  ProfileWireResponse,
+  EncryptedFieldWire,
   CreateAppointmentRequest,
   UpdateAppointmentRequest,
 } from '../types/api';
@@ -213,47 +215,48 @@ class ApiService {
     return response.data;
   }
 
-  // ---- Profile (Phase 3c) ----
+  // ---- Profile (zero-knowledge: opaque encrypted name) ----
 
-  async getProfile(): Promise<Profile> {
-    const response = await this.client.get<Profile>('/profiles/me');
+  async getProfile(): Promise<ProfileWireResponse> {
+    const response = await this.client.get<ProfileWireResponse>('/profiles/me');
     return response.data;
   }
 
-  async updateProfileName(name: string): Promise<Profile> {
-    const response = await this.client.put<Profile>('/profiles/me', { name });
+  async updateProfileName(nameData: string, nameIv: string): Promise<ProfileWireResponse> {
+    const response = await this.client.put<ProfileWireResponse>('/profiles/me', {
+      name_data: nameData,
+      name_iv: nameIv,
+    });
     return response.data;
   }
 
-  // ---- Medications ----
+  // ---- Medications (zero-knowledge: opaque encrypted blobs) ----
 
-  async getMedications(): Promise<Medication[]> {
-    const response = await this.client.get<Medication[]>('/medications');
+  async getMedications(): Promise<MedicationWireResponse[]> {
+    const response = await this.client.get<MedicationWireResponse[]>('/medications');
     return response.data;
   }
 
-  async getMedication(id: string): Promise<Medication> {
-    const response = await this.client.get<Medication>(`/medications/${id}`);
+  async getMedication(id: string): Promise<MedicationWireResponse> {
+    const response = await this.client.get<MedicationWireResponse>(`/medications/${id}`);
     return response.data;
   }
 
-  async createMedication(data: CreateMedicationRequest): Promise<Medication> {
-    const response = await this.client.post<Medication>('/medications', data);
+  async createMedication(data: CreateMedicationRequest): Promise<MedicationWireResponse> {
+    const response = await this.client.post<MedicationWireResponse>('/medications', data);
     return response.data;
   }
 
-  async updateMedication(id: string, data: UpdateMedicationRequest): Promise<Medication> {
-    // Backend update is POST /:id (not PUT).
-    const response = await this.client.post<Medication>(`/medications/${id}`, data);
+  async updateMedication(id: string, data: UpdateMedicationRequest): Promise<MedicationWireResponse> {
+    const response = await this.client.post<MedicationWireResponse>(`/medications/${id}`, data);
     return response.data;
   }
 
   async deleteMedication(id: string): Promise<void> {
-    // Backend delete is POST /:id/delete (not DELETE /:id).
     await this.client.post(`/medications/${id}/delete`);
   }
 
-  // ---- Dose logging + adherence (Phase 3c) ----
+  // ---- Dose logging + adherence (not encrypted — counts/flags only) ----
 
   async logDose(medicationId: string, req: LogDoseRequest): Promise<DoseLog> {
     const response = await this.client.post<DoseLog>(`/medications/${medicationId}/log`, req);
@@ -265,27 +268,27 @@ class ApiService {
     return response.data;
   }
 
-  // ---- Appointments ----
+  // ---- Appointments (zero-knowledge: opaque encrypted blobs) ----
 
-  async getAppointments(status?: string): Promise<Appointment[]> {
-    const response = await this.client.get<Appointment[]>('/appointments', {
+  async getAppointments(status?: string): Promise<AppointmentWireResponse[]> {
+    const response = await this.client.get<AppointmentWireResponse[]>('/appointments', {
       params: status ? { status } : undefined,
     });
     return response.data;
   }
 
-  async getAppointment(id: string): Promise<Appointment> {
-    const response = await this.client.get<Appointment>(`/appointments/${id}`);
+  async getAppointment(id: string): Promise<AppointmentWireResponse> {
+    const response = await this.client.get<AppointmentWireResponse>(`/appointments/${id}`);
     return response.data;
   }
 
-  async createAppointment(data: CreateAppointmentRequest): Promise<Appointment> {
-    const response = await this.client.post<Appointment>('/appointments', data);
+  async createAppointment(data: CreateAppointmentRequest): Promise<AppointmentWireResponse> {
+    const response = await this.client.post<AppointmentWireResponse>('/appointments', data);
     return response.data;
   }
 
-  async updateAppointment(id: string, data: UpdateAppointmentRequest): Promise<Appointment> {
-    const response = await this.client.post<Appointment>(`/appointments/${id}`, data);
+  async updateAppointment(id: string, data: UpdateAppointmentRequest): Promise<AppointmentWireResponse> {
+    const response = await this.client.post<AppointmentWireResponse>(`/appointments/${id}`, data);
     return response.data;
   }
 
diff --git a/web/normogen-web/src/store/useStore.test.ts b/web/normogen-web/src/store/useStore.test.ts
index 2af1974..5024b07 100644
--- a/web/normogen-web/src/store/useStore.test.ts
+++ b/web/normogen-web/src/store/useStore.test.ts
@@ -1,4 +1,6 @@
 import { describe, it, expect, beforeEach, vi } from 'vitest';
+import { deriveAuthAndEncKeys, setEncKey, clearEncKey } from '../crypto';
+import { encryptJson } from '../crypto';
 
 // Mock the api client so the store's real reducer logic is exercised without HTTP.
 const apiMock = {
@@ -13,52 +15,87 @@ vi.mock('../services/api', () => ({ default: apiMock }));
 const { useMedicationStore } = await import('./useStore');
 
 describe('useMedicationStore', () => {
-  beforeEach(() => {
+  let encKey: CryptoKey;
+
+  beforeEach(async () => {
+    // Derive a real encryption key so the store can encrypt/decrypt.
+    const { encKey: key } = await deriveAuthAndEncKeys('test-password');
+    encKey = key;
+    setEncKey(encKey);
+
     useMedicationStore.setState({
       medications: [],
       isLoading: false,
       error: null,
       adherence: {},
+      selectedMedication: null,
     });
     apiMock.getMedications.mockReset();
     apiMock.createMedication.mockReset();
   });
 
-  it('loadMedications populates state from the api client', async () => {
-    const meds = [{ medication_id: 'm1', name: 'Aspirin', dosage: '100mg' }];
-    apiMock.getMedications.mockResolvedValue(meds);
+  afterEach(() => {
+    clearEncKey();
+  });
+
+  it('loadMedications decrypts wire responses into domain medications', async () => {
+    // The API returns opaque wire blobs; the store decrypts them.
+    const blob = await encryptJson({ name: 'Aspirin', dosage: '100mg', frequency: 'daily' }, encKey);
+    apiMock.getMedications.mockResolvedValue([
+      {
+        id: 'oid1',
+        medication_id: 'm1',
+        user_id: 'u1',
+        profile_id: 'p1',
+        active: true,
+        encrypted_data: blob,
+        created_at: '2026-01-01T00:00:00Z',
+        updated_at: '2026-01-01T00:00:00Z',
+      },
+    ]);
 
     await useMedicationStore.getState().loadMedications();
 
     expect(apiMock.getMedications).toHaveBeenCalledOnce();
-    expect(useMedicationStore.getState().medications).toEqual(meds);
-    expect(useMedicationStore.getState().isLoading).toBe(false);
+    const meds = useMedicationStore.getState().medications;
+    expect(meds).toHaveLength(1);
+    expect(meds[0].name).toBe('Aspirin');
+    expect(meds[0].dosage).toBe('100mg');
+    expect(meds[0].active).toBe(true);
   });
 
-  it('loadMedications sets an error message on failure (and does not throw)', async () => {
-    apiMock.getMedications.mockRejectedValue(new Error('boom'));
-
-    // Should NOT throw — load actions swallow.
+  it('loadMedications sets an error when no enc key is available', async () => {
+    clearEncKey();
     await useMedicationStore.getState().loadMedications();
-
-    expect(useMedicationStore.getState().error).toBe('boom');
-    expect(useMedicationStore.getState().isLoading).toBe(false);
+    expect(useMedicationStore.getState().error).toMatch(/No encryption key/);
   });
 
-  it('createMedication appends the new medication and re-throws on error', async () => {
-    apiMock.createMedication.mockResolvedValue({ medication_id: 'm2', name: 'New' });
+  it('createMedication encrypts domain data and stores the decrypted result', async () => {
+    const blob = await encryptJson({ name: 'New', dosage: '50mg', frequency: 'daily' }, encKey);
+    apiMock.createMedication.mockResolvedValue({
+      id: 'oid2',
+      medication_id: 'm2',
+      user_id: 'u1',
+      profile_id: 'p1',
+      active: true,
+      encrypted_data: blob,
+      created_at: '2026-01-01T00:00:00Z',
+      updated_at: '2026-01-01T00:00:00Z',
+    });
 
-    await useMedicationStore.getState().createMedication({ name: 'New' });
+    await useMedicationStore.getState().createMedication({
+      name: 'New',
+      dosage: '50mg',
+      frequency: 'daily',
+      route: 'oral',
+      profile_id: 'p1',
+      active: true,
+    });
 
-    expect(useMedicationStore.getState().medications).toEqual([
-      { medication_id: 'm2', name: 'New' },
-    ]);
-
-    // Now an error path: createMedication rejects -> store re-throws.
-    apiMock.createMedication.mockRejectedValue(new Error('nope'));
-    await expect(
-      useMedicationStore.getState().createMedication({ name: 'Bad' }),
-    ).rejects.toThrow('nope');
+    const meds = useMedicationStore.getState().medications;
+    expect(meds).toHaveLength(1);
+    expect(meds[0].name).toBe('New');
+    expect(meds[0].dosage).toBe('50mg');
   });
 
   it('logDose logs the dose then refreshes adherence', async () => {
diff --git a/web/normogen-web/src/store/useStore.ts b/web/normogen-web/src/store/useStore.ts
index d471874..3e19a04 100644
--- a/web/normogen-web/src/store/useStore.ts
+++ b/web/normogen-web/src/store/useStore.ts
@@ -1,5 +1,13 @@
 import { create } from 'zustand';
 import { devtools, persist } from 'zustand/middleware';
+import {
+  deriveAuthAndEncKeys,
+  setEncKey,
+  clearEncKey,
+  getEncKey,
+  encryptJson,
+  decryptJson,
+} from '../crypto';
 import {
   User,
   Medication,
@@ -88,8 +96,10 @@ interface AppointmentState {
   isLoading: boolean;
   error: string | null;
   loadAppointments: (status?: string) => Promise<void>;
-  createAppointment: (data: CreateAppointmentRequest) => Promise<void>;
-  updateAppointment: (id: string, data: UpdateAppointmentRequest) => Promise<void>;
+  // The store receives DOMAIN data (decrypted fields from the UI) and encrypts
+  // it internally before sending to the server.
+  createAppointment: (data: Record<string, unknown>) => Promise<void>;
+  updateAppointment: (id: string, data: Record<string, unknown>) => Promise<void>;
   deleteAppointment: (id: string) => Promise<void>;
   clearError: () => void;
 }
@@ -108,7 +118,11 @@ export const useAuthStore = create<AuthState>()(
         login: async (email: string, password: string) => {
           set({ isLoading: true, error: null });
           try {
-            const response = await apiService.login(email, password);
+            // Zero-knowledge: derive auth secret + encryption key from password.
+            const { authSecret, encKey } = await deriveAuthAndEncKeys(password);
+            setEncKey(encKey);
+            // Send the derived auth secret (not the raw password) to the server.
+            const response = await apiService.login(email, authSecret);
             set({
               user: {
                 user_id: response.user_id,
@@ -121,6 +135,7 @@ export const useAuthStore = create<AuthState>()(
               isLoading: false,
             });
           } catch (error: any) {
+            clearEncKey();
             set({
               error: error.message || 'Login failed',
               isLoading: false,
@@ -133,11 +148,12 @@ export const useAuthStore = create<AuthState>()(
         register: async (username: string, email: string, password: string) => {
           set({ isLoading: true, error: null });
           try {
+            const { authSecret, encKey } = await deriveAuthAndEncKeys(password);
+            setEncKey(encKey);
             const response = await apiService.register({
               username,
               email,
-              password,
-              role: 'patient',
+              password: authSecret,
             });
             set({
               user: {
@@ -161,6 +177,7 @@ export const useAuthStore = create<AuthState>()(
         },
 
         logout: async () => {
+          clearEncKey();
           await apiService.logout();
           set({
             user: null,
@@ -215,9 +232,42 @@ export const useMedicationStore = create<MedicationState>()(
     adherence: {},
 
     loadMedications: async () => {
+      const key = getEncKey();
+      if (!key) {
+        set({ error: 'No encryption key — log in to decrypt data', isLoading: false });
+        return;
+      }
       set({ isLoading: true, error: null });
       try {
-        const medications = await apiService.getMedications();
+        const wireMeds = await apiService.getMedications();
+        // Decrypt each opaque blob into domain Medication objects.
+        const medications = await Promise.all(
+          wireMeds.map(async (w) => {
+            const data = await decryptJson<Record<string, unknown>>(w.encrypted_data, key);
+            return {
+              id: w.id,
+              medication_id: w.medication_id,
+              user_id: w.user_id,
+              profile_id: w.profile_id,
+              name: (data.name as string) ?? '',
+              dosage: (data.dosage as string) ?? '',
+              frequency: (data.frequency as string) ?? '',
+              route: data.route as string | undefined,
+              reason: data.reason as string | undefined,
+              instructions: data.instructions as string | undefined,
+              side_effects: data.sideEffects as string[] | undefined,
+              prescribed_by: data.prescribedBy as string | undefined,
+              prescribed_date: data.prescribedDate as string | undefined,
+              start_date: data.startDate as string | undefined,
+              end_date: data.endDate as string | undefined,
+              notes: data.notes as string | undefined,
+              tags: data.tags as string[] | undefined,
+              active: w.active,
+              created_at: w.created_at,
+              updated_at: w.updated_at,
+            } as Medication;
+          }),
+        );
         set({ medications, isLoading: false });
       } catch (error: any) {
         set({
@@ -228,9 +278,42 @@ export const useMedicationStore = create<MedicationState>()(
     },
 
     createMedication: async (data: any) => {
+      const key = getEncKey();
+      if (!key) {
+        set({ error: 'No encryption key — cannot encrypt data' });
+        throw new Error('No encryption key');
+      }
       set({ isLoading: true, error: null });
       try {
-        const medication = await apiService.createMedication(data);
+        // Encrypt the domain fields into an opaque blob.
+        const { name, dosage, frequency, route, reason, instructions,
+          side_effects, prescribed_by, prescribed_date, start_date,
+          end_date, notes, tags, ...rest } = data;
+        const encrypted_data = await encryptJson({
+          name, dosage, frequency, route, reason, instructions,
+          sideEffects: side_effects, prescribedBy: prescribed_by,
+          prescribedDate: prescribed_date, startDate: start_date,
+          endDate: end_date, notes, tags,
+        }, key);
+        const wire = await apiService.createMedication({
+          profile_id: data.profile_id,
+          encrypted_data,
+          active: data.active,
+        });
+        // Decrypt the response back into a domain Medication for the store.
+        const decrypted = await decryptJson<Record<string, unknown>>(wire.encrypted_data, key);
+        const medication = {
+          id: wire.id,
+          medication_id: wire.medication_id,
+          user_id: wire.user_id,
+          profile_id: wire.profile_id,
+          name: (decrypted.name as string) ?? '',
+          dosage: (decrypted.dosage as string) ?? '',
+          frequency: (decrypted.frequency as string) ?? '',
+          active: wire.active,
+          created_at: wire.created_at,
+          updated_at: wire.updated_at,
+        } as Medication;
         set((state) => ({
           medications: [...state.medications, medication],
           isLoading: false,
@@ -245,12 +328,33 @@ export const useMedicationStore = create<MedicationState>()(
     },
 
     updateMedication: async (id: string, data: any) => {
+      const key = getEncKey();
+      if (!key) {
+        set({ error: 'No encryption key — cannot encrypt data' });
+        throw new Error('No encryption key');
+      }
       set({ isLoading: true, error: null });
       try {
-        const updated = await apiService.updateMedication(id, data);
+        // Encrypt the full updated domain record into a new blob.
+        const { name, dosage, frequency, route, reason, instructions,
+          side_effects, prescribed_by, prescribed_date, start_date,
+          end_date, notes, tags } = data;
+        const encrypted_data = await encryptJson({
+          name, dosage, frequency, route, reason, instructions,
+          sideEffects: side_effects, prescribedBy: prescribed_by,
+          prescribedDate: prescribed_date, startDate: start_date,
+          endDate: end_date, notes, tags,
+        }, key);
+        const wire = await apiService.updateMedication(id, {
+          encrypted_data,
+          active: data.active,
+        });
+        // Update the domain medication in the store.
         set((state) => ({
           medications: state.medications.map((med) =>
-            med.medication_id === id ? updated : med
+            med.medication_id === id
+              ? { ...med, ...data, updated_at: wire.updated_at }
+              : med,
           ),
           isLoading: false,
         }));
@@ -451,9 +555,30 @@ export const useProfileStore = create<ProfileState>()(
     error: null,
 
     loadProfile: async () => {
+      const key = getEncKey();
+      if (!key) {
+        set({ error: 'No encryption key — log in to decrypt data', isLoading: false });
+        return;
+      }
       set({ isLoading: true, error: null });
       try {
-        const profile = await apiService.getProfile();
+        const wire = await apiService.getProfile();
+        // Decrypt the profile name.
+        let name = '';
+        if (wire.name_data && wire.name_iv) {
+          try {
+            name = await decryptJson<string>({ data: wire.name_data, iv: wire.name_iv }, key);
+          } catch { name = ''; }
+        }
+        const profile: Profile = {
+          profile_id: wire.profile_id,
+          user_id: wire.user_id,
+          name,
+          role: wire.role,
+          permissions: wire.permissions,
+          created_at: wire.created_at,
+          updated_at: wire.updated_at,
+        };
         set({ profile, isLoading: false });
       } catch (error: any) {
         set({
@@ -464,9 +589,28 @@ export const useProfileStore = create<ProfileState>()(
     },
 
     updateName: async (name) => {
+      const key = getEncKey();
+      if (!key) {
+        set({ error: 'No encryption key — cannot encrypt data' });
+        throw new Error('No encryption key');
+      }
       set({ isLoading: true, error: null });
       try {
-        const profile = await apiService.updateProfileName(name);
+        const blob = await encryptJson(name, key);
+        const wire = await apiService.updateProfileName(blob.data, blob.iv);
+        let decryptedName = name;
+        try {
+          decryptedName = await decryptJson<string>({ data: wire.name_data, iv: wire.name_iv }, key);
+        } catch { /* keep the input name */ }
+        const profile: Profile = {
+          profile_id: wire.profile_id,
+          user_id: wire.user_id,
+          name: decryptedName,
+          role: wire.role,
+          permissions: wire.permissions,
+          created_at: wire.created_at,
+          updated_at: wire.updated_at,
+        };
         set({ profile, isLoading: false });
       } catch (error: any) {
         set({
@@ -489,9 +633,36 @@ export const useAppointmentStore = create<AppointmentState>()(
     error: null,
 
     loadAppointments: async (status) => {
+      const key = getEncKey();
+      if (!key) {
+        set({ error: 'No encryption key — log in to decrypt data', isLoading: false });
+        return;
+      }
       set({ isLoading: true, error: null });
       try {
-        const appointments = await apiService.getAppointments(status);
+        const wireAppts = await apiService.getAppointments(status);
+        const appointments = await Promise.all(
+          wireAppts.map(async (w) => {
+            const data = await decryptJson<Record<string, unknown>>(w.encrypted_data, key);
+            return {
+              id: w.id,
+              appointment_id: w.appointment_id,
+              user_id: w.user_id,
+              profile_id: w.profile_id,
+              title: (data.title as string) ?? '',
+              provider: (data.provider as string) ?? '',
+              appointment_type: (data.appointmentType as string) ?? '',
+              date_time: (data.dateTime as string) ?? '',
+              location: data.location as string | undefined,
+              duration_minutes: data.durationMinutes as number | undefined,
+              reason: data.reason as string | undefined,
+              notes: data.notes as string | undefined,
+              status: w.status,
+              created_at: w.created_at,
+              updated_at: w.updated_at,
+            } as Appointment;
+          }),
+        );
         set({ appointments, isLoading: false });
       } catch (error: any) {
         set({
@@ -502,11 +673,40 @@ export const useAppointmentStore = create<AppointmentState>()(
     },
 
     createAppointment: async (data) => {
+      const key = getEncKey();
+      if (!key) {
+        set({ error: 'No encryption key — cannot encrypt data' });
+        throw new Error('No encryption key');
+      }
       set({ isLoading: true, error: null });
       try {
-        const appt = await apiService.createAppointment(data);
+        const d = data as any;
+        const { title, provider, appointment_type, date_time, location,
+          duration_minutes, reason, notes } = d;
+        const encrypted_data = await encryptJson({
+          title, provider, appointmentType: appointment_type,
+          dateTime: date_time, location, durationMinutes: duration_minutes,
+          reason, notes,
+        }, key);
+        const wire = await apiService.createAppointment({
+          profile_id: d.profile_id,
+          encrypted_data,
+          status: d.status,
+        });
+        // Build the domain Appointment for the store.
+        const appointment: Appointment = {
+          appointment_id: wire.appointment_id,
+          id: wire.id,
+          user_id: wire.user_id,
+          profile_id: wire.profile_id,
+          title, provider, appointment_type, date_time,
+          location, duration_minutes, reason, notes,
+          status: wire.status,
+          created_at: wire.created_at,
+          updated_at: wire.updated_at,
+        };
         set((state) => ({
-          appointments: [...state.appointments, appt],
+          appointments: [...state.appointments, appointment],
           isLoading: false,
         }));
       } catch (error: any) {
@@ -519,11 +719,29 @@ export const useAppointmentStore = create<AppointmentState>()(
     },
 
     updateAppointment: async (id, data) => {
+      const key = getEncKey();
+      if (!key) {
+        set({ error: 'No encryption key — cannot encrypt data' });
+        throw new Error('No encryption key');
+      }
       try {
-        const updated = await apiService.updateAppointment(id, data);
+        const d = data as any;
+        const { title, provider, appointment_type, date_time, location,
+          duration_minutes, reason, notes } = d;
+        const encrypted_data = await encryptJson({
+          title, provider, appointmentType: appointment_type,
+          dateTime: date_time, location, durationMinutes: duration_minutes,
+          reason, notes,
+        }, key);
+        const wire = await apiService.updateAppointment(id, {
+          encrypted_data,
+          status: d.status,
+        });
         set((state) => ({
           appointments: state.appointments.map((a) =>
-            a.appointment_id === id ? updated : a,
+            a.appointment_id === id
+              ? { ...a, ...data, status: wire.status, updated_at: wire.updated_at }
+              : a,
           ),
         }));
       } catch (error: any) {
diff --git a/web/normogen-web/src/types/api.ts b/web/normogen-web/src/types/api.ts
index 6ba868e..62918ad 100644
--- a/web/normogen-web/src/types/api.ts
+++ b/web/normogen-web/src/types/api.ts
@@ -110,6 +110,14 @@ export interface PillIdentification {
   custom_color?: string;
 }
 
+// ---- Opaque encrypted blob wire types (zero-knowledge) ----
+export interface EncryptedFieldWire {
+  data: string;
+  iv: string;
+  auth_tag?: string;
+}
+
+// ---- Medication: domain type (decrypted, used by UI) ----
 export interface Medication {
   id?: string;
   medication_id?: string;
@@ -129,39 +137,32 @@ export interface Medication {
   notes?: string;
   tags?: string[];
   active: boolean;
-  pill_identification?: PillIdentification;
   created_at?: string;
   updated_at?: string;
 }
 
-export interface CreateMedicationRequest {
-  name: string;
-  dosage: string;
-  frequency: string;
-  route: string;
+// Medication wire response (opaque blob from the server)
+export interface MedicationWireResponse {
+  id: string;
+  medication_id: string;
+  user_id: string;
   profile_id: string;
-  reason?: string;
-  instructions?: string;
-  side_effects?: string[];
-  prescribed_by?: string;
-  prescribed_date?: string;
-  start_date?: string;
-  end_date?: string;
-  notes?: string;
-  tags?: string[];
-  reminder_times?: string[];
-  pill_identification?: PillIdentification;
+  active: boolean;
+  encrypted_data: EncryptedFieldWire;
+  created_at: string;
+  updated_at: string;
+}
+
+// Medication create/update requests (send encrypted blob to the server)
+export interface CreateMedicationRequest {
+  profile_id: string;
+  encrypted_data: EncryptedFieldWire;
+  active?: boolean;
 }
 
 export interface UpdateMedicationRequest {
-  name?: string;
-  dosage?: string;
-  frequency?: string;
-  start_date?: string;
-  end_date?: string;
-  instructions?: string;
+  encrypted_data?: EncryptedFieldWire;
   active?: boolean;
-  pill_identification?: PillIdentification;
 }
 
 // Drug Interaction Types (Phase 2.8)
@@ -244,7 +245,7 @@ export interface LabResult {
   created_at?: string;
 }
 
-// Appointment Types — match backend AppointmentResponse (snake_case).
+// Appointment: domain type (decrypted, used by UI)
 export interface Appointment {
   id?: string;
   appointment_id: string;
@@ -263,31 +264,41 @@ export interface Appointment {
   updated_at?: string;
 }
 
-export interface CreateAppointmentRequest {
-  title: string;
-  provider: string;
-  appointment_type: string;
-  date_time: string;
+// Appointment wire response (opaque blob)
+export interface AppointmentWireResponse {
+  id: string;
+  appointment_id: string;
+  user_id: string;
   profile_id: string;
-  location?: string;
-  duration_minutes?: number;
-  reason?: string;
-  notes?: string;
+  status: string;
+  encrypted_data: EncryptedFieldWire;
+  created_at: string;
+  updated_at: string;
+}
+
+export interface CreateAppointmentRequest {
+  profile_id: string;
+  encrypted_data: EncryptedFieldWire;
   status?: string;
 }
 
 export interface UpdateAppointmentRequest {
-  title?: string;
-  provider?: string;
-  appointment_type?: string;
-  date_time?: string;
-  location?: string;
-  duration_minutes?: number;
-  reason?: string;
-  notes?: string;
+  encrypted_data?: EncryptedFieldWire;
   status?: string;
 }
 
+// Profile wire response (opaque encrypted name)
+export interface ProfileWireResponse {
+  profile_id: string;
+  user_id: string;
+  name_data: string;
+  name_iv: string;
+  role: string;
+  permissions: string[];
+  created_at: string;
+  updated_at: string;
+}
+
 // Dose Log Types — match backend MedicationDose (camelCase serialization).
 export interface DoseLog {
   id?: string;